ATTORNEY ADVERTISING. Depo-Provera Help is an advertising and referral service operated by TFT Legal Service. We are not a law firm and do not give legal or medical advice. Submitting information does not create an attorney-client relationship.

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Free case review · United States

Diagnosed With a Meningioma After Depo-Provera Shots?

If you received Depo-Provera (or a generic depot medroxyprogesterone acetate injection) and were later diagnosed with a meningioma brain tumor, you may have legal options. A participating attorney can review your situation for free.

Your questions matter. Getting answers costs nothing.

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  • Free and confidential
  • No obligation
  • Takes a few minutes
Free case reviews for people across the United States.Deadlines to file vary by state, so it may help to ask soon.
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What this is about

Depo-Provera and meningioma: why people are asking questions

Depo-Provera is a hormone injection that contains depot medroxyprogesterone acetate (MPA). In recent years, researchers have studied whether long-term use of MPA is linked to meningioma, a usually non-cancerous tumor that grows from the membranes around the brain and spinal cord.

A large study published in The BMJ in 2024 found that using injectable MPA for a year or more was associated with a substantially higher risk of meningioma needing surgery. People who were diagnosed after using the shot have since filed lawsuits.

about 5.6×

higher odds of a meningioma needing surgery were linked to using injectable MPA for a year or more, in one national case-control study (The BMJ, 2024). It found an association, not proof of cause.

MDL 3140

On February 7, 2025, federal Depo-Provera meningioma cases were centralized in the U.S. District Court for the Northern District of Florida (Pensacola).

1992

is the year the FDA approved Depo-Provera as a birth control injection. It is usually given about every 12 weeks.

The study found an association; it does not show that Depo-Provera caused any individual person’s tumor. Only your doctor can speak to your medical situation, and only an attorney can evaluate a legal claim.

Sources

  1. Roland N. et al., “Use of progestogens and the risk of intracranial meningioma: national case-control study,” The BMJ, March 2024 (BMJ 2024;384:e078078) (opens in a new tab)
  2. U.S. District Court, Northern District of Florida: MDL No. 3140, In re: Depo-Provera (Depot Medroxyprogesterone Acetate) Products Liability Litigation (case page, orders and updates) (opens in a new tab)
A woman discusses her test results with a clinicianGiven about every 12 weeks
About the shot

What is Depo-Provera?

Depo-Provera is a prescription birth control injection approved by the U.S. Food and Drug Administration (FDA) in 1992. It is usually given in the arm or buttock about every 12 weeks. A lower-dose version, Depo-SubQ Provera 104, is injected under the skin, and generic versions of depot MPA are also available. It works mainly by preventing ovulation.

Besides birth control, doctors may prescribe it for other conditions, including:

  • Birth control
  • Endometriosis
  • Chronic pelvic pain
  • Menstrual disorders
  • Hormonal imbalances
  • Uterine fibroids
  • Some cancer treatments

How might MPA be connected to meningioma?

MPA is a synthetic form of the hormone progesterone. Many meningiomas have progesterone receptors, and researchers think MPA may act on those receptors in the meninges (the protective layers around the brain and spinal cord), which could encourage abnormal cell growth. Research on this question is ongoing.

Please do not stop or change any prescribed medication without talking to your doctor. This site does not give medical advice.

Warning signs

Common symptoms of meningioma

Meningiomas often grow slowly, and symptoms depend on the tumor’s size and location. Some people have no symptoms at first.

  • Headachesoften worse in the morning
  • Vision changesblurred or double vision
  • Hearing lossin one or both ears
  • Tinnitusringing in the ears
  • Memory lossor trouble concentrating
  • Confusionor feeling disoriented
  • Seizuresnew or unexplained
  • Balance problemsloss of balance or vertigo
  • Loss of smellreduced sense of smell
  • Weakness or numbnessin the arms or legs
  • Trouble speakingfinding or forming words

These symptoms can have many causes. If you notice any of them, talk to your doctor. If you have sudden severe symptoms, such as a seizure or sudden vision loss, call 911 or go to the nearest emergency room.

The lawsuits

What is a Depo-Provera lawsuit?

People diagnosed with a meningioma after using Depo-Provera have filed product liability lawsuits against Pfizer, the maker of Depo-Provera, and related companies. The lawsuits allege that the company knew or should have known about the meningioma risk and failed to adequately warn doctors and patients.

On February 7, 2025, the Judicial Panel on Multidistrict Litigation centralized the federal cases in In re: Depo-Provera (Depot Medroxyprogesterone Acetate) Products Liability Litigation, MDL No. 3140, in the U.S. District Court for the Northern District of Florida in Pensacola.

Court orders entered in mid-2026 describe a confidential settlement program between plaintiffs’ lead counsel and Pfizer/Pharmacia for eligible plaintiffs whose cases are pending in the MDL. Eligibility is not automatic, and other claims continue in litigation. An attorney can explain whether any program or deadline may apply to you.

You may be eligible for a free case review if:

  • You received Depo-Provera or a generic depot MPA injection (including Depo-SubQ Provera 104)
  • You were later diagnosed with a meningioma (brain tumor)
  • Diagnosis or treatment records may help, but you do not need them to start

Deadlines vary by state. Some law firms also look at how many injections you received and for how long; the attorney will evaluate your history. Only a licensed attorney can determine whether you have a valid claim.

Check if you qualify
How it works

Three simple steps

Requesting a free review takes a few minutes, and you decide what happens next.

  1. 01

    Start your free review

    Open the short case review form on this page and share some basic details. It takes just a few minutes.

  2. 02

    A law firm follows up

    A participating law firm or its intake team may contact you privately to ask about your Depo-Provera injections and your diagnosis.

  3. 03

    Learn your options

    An attorney can review your situation and explain whether you may have a claim and what happens next. There is no obligation.

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Private from the start

The case review form opens right on this page. You can stop at any time, and you decide whether to submit your contact details.

Check if you qualify

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What to expect

Support at your pace

A brain tumor diagnosis can turn life upside down. Looking into your legal options should not add to the stress, so we keep the process simple and respectful.

  • Private and respectful

    Your health history is personal. the form is short, you can stop at any time, and you decide whether to submit your contact details.

  • Attorneys who handle these cases

    Your information goes to a participating law firm that reviews Depo-Provera meningioma claims and can explain the process in plain language.

  • No cost to get a review

    There is no charge for a case review. These cases are often handled on a contingency-fee basis, but fee terms and case costs vary, so ask the attorney and read the agreement before you sign.

  • Help with records

    You do not need your records to start. If you continue, the law firm can often help you request injection and diagnosis records from your providers.

Who we are

An advertising and referral service, not a law firm

Depo-Provera Help is operated by TFT Legal Service, a legal marketing and referral service. We do not give legal or medical advice, and we do not represent anyone. When you ask for a review, your information is forwarded to a participating law firm, which decides whether to contact you and whether to offer representation.

Submitting information does not create an attorney-client relationship. Every case is different, no particular outcome can be promised, and only a licensed attorney can determine whether you have a valid claim.

Questions

Frequently asked questions

Straight answers about how this works. If you are unsure about anything, ask the attorney before you sign.

Is this a law firm?

No. Depo-Provera Help is an attorney advertising and referral service operated by TFT Legal Service. We are not a law firm and do not give legal advice. If you ask for a review, your information is shared with a participating attorney or law firm, who decides whether to offer representation. Only a licensed attorney can tell you whether you have a valid claim.

Does it cost anything?

No. Answering the questions and having your situation reviewed is free. Attorneys who handle these cases often work on a contingency-fee basis, which typically means no attorney fee unless there is a recovery. Fee terms and case costs vary, so ask the attorney and read any agreement before you sign.

What is a meningioma?

A meningioma is a tumor that grows from the meninges, the protective layers around the brain and spinal cord. Most are not cancerous, but they can press on the brain, nerves or blood vessels and cause symptoms such as headaches, vision changes or seizures. Some need surgery or radiation. Your doctor is the right person to explain your diagnosis.

Do I need my medical records now?

No. Records are helpful but not required to start. If you continue, records showing your Depo-Provera injections and your meningioma diagnosis or treatment may help the attorney evaluate your claim, and the law firm can often help you request them.

Is there a deadline?

Yes. Every state sets time limits (statutes of limitations) for filing a claim, and they vary by state and by the facts, such as when you were diagnosed. Because deadlines can pass quickly, it is a good idea to ask an attorney soon.

Is there a settlement?

Court orders entered in the federal Depo-Provera litigation (MDL No. 3140) in mid-2026 describe a confidential settlement program between plaintiffs’ lead counsel and Pfizer/Pharmacia for eligible plaintiffs whose cases are pending in the MDL. Eligibility is not automatic, and other claims continue in litigation. We cannot say whether you would qualify or what any amount might be. An attorney can explain whether any program or deadline may apply to you.

What happens after I answer the questions?

If you submit the form with your contact details, a participating law firm or its intake team may contact you by phone, text or email to learn more about your Depo-Provera use and your diagnosis. You decide whether to continue. There is no obligation, and no particular outcome can be promised.

Will my information be kept private?

Your information is used to respond to your request and is shared only with participating attorneys and the service providers that help run this website (including the provider of the questionnaire), as described in our Privacy Policy. Submitting information does not create an attorney-client relationship.

Get answers about your options

If you were diagnosed with a meningioma after Depo-Provera injections, request a free, confidential case review. It is free, and you are under no obligation.

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